8,968 research outputs found

    Six topics on inscribable polytopes

    Full text link
    Inscribability of polytopes is a classic subject but also a lively research area nowadays. We illustrate this with a selection of well-known results and recent developments on six particular topics related to inscribable polytopes. Along the way we collect a list of (new and old) open questions.Comment: 11 page

    Clinician acquisition and retention of Motivational Interviewing skills: a two-and-a-half-year exploratory study

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>Motivational interviewing (MI) is a collaborative, client-centred counselling style aimed at eliciting and strengthening clients' intrinsic motivation to change. There is strong research evidence supporting the efficacy of MI, notably in its application among alcohol and drug abuse populations. MI interventions in smoking cessation may yield modest but significant increases in quitting. The present study sought to assess the acquisition and retention of MI skills in counsellors at the Swedish National Tobacco Quitline.</p> <p>Methods</p> <p>Three audio-recorded sessions from each of three counsellors were assessed using the Motivational Interviewing Treatment Integrity (MITI) Code Version 3.0 over 11 assessment periods at fixed intervals in a two-and-a-half year period during which counsellors received ongoing supervision.</p> <p>Results</p> <p>The mean skill for all counsellors improved throughout the study period in most MITI variables. However, great variations in MI skill between counsellors were observed, as well as fluctuations in performance in counsellors over time.</p> <p>Conclusion</p> <p>The present exploratory study covers a longer time period than most evaluations of MI training, and has several advantages with regard to study design. It may provide a basis for (larger sample) replication to test MI skill (as measured by the MITI) in relation to behaviour change in clients, to evaluate MI training, and to assess the acquisition and retention of MI skill over time. Difficulties in acquiring and retaining MI skill may raise the issue of a selection policy for MI training. Moreover, fluctuations in MI skill over time emphasise the greater importance of continuous feedback and supervision over initial MI training, and the need for the use of validated treatment integrity assessment instruments in ordinary clinical implementations of MI.</p

    Localization of Fulicin-like Immunoreactivity in the Central Nervous System and Periphery of Biomphalaria glabrata, an Intermediate Host for Schistosomiasis

    Full text link
    An estimate of about ten percent of the population worldwide live at risk of contracting the parasitic disease schistosomiasis, or “snail fever”. The digenetic trematode worm species Schistosoma mansoni that is responsible for causing the most common form of intestinal schistosomiasis requires the freshwater snail Biomphalaria glabrata to serve as its primary intermediate host, where it multiplies and develops into its cercarial form that is infectious to humans. Parasitic castration and parasitic gigantism are among some of the profound behavioral changes that the infection of B. glabrata by S. mansoni is known to cause. For this reason, a neural transcriptomics approach was undertaken to determine precursor prohormones that could encode neuropeptides implicated in Biomphalaria reproductive and feeding behaviors. A transcript (1616 nucleotides) was found to encode a putative precursor polypeptide (316 aminoacids) that could give way to the neuropeptide fulicin (Phe–D-Asn-Glu-Phe-Val-NH2; Ohta et al. 1991; Yasuma Kamatani et al. 1995) and five additional related peptides. For this investigation, affinity purified polyclonal antibodies (rabbit) were developed against the anticipated fulicin neuropeptide. Fulicin-like immunoreactivity was observed throughout the central nervous system (CNS) with distinct neurons and clusters on the ventral and dorsal surfaces, as well as in peripheral tissues. Fulicin-like cells of both large and small diameter were present on the dorsal and ventral surfaces of the buccal ganglion. In addition dispersed clusters of small diameter cells were observed in the cerebral and pedal ganglia. However, in the right pleural ganglion no fulicin-like neurons were present, although it was rich in immunoreactive fibers. Within the left parietal and visceral ganglia, clusters of large prominent cells appeared to give rise to axons projecting to the anal and intestinal nerves. Additionally, peripheral tissue of B. glabrata, specifically regions of the mantle, lip and tentacle were rich in fulicin-like immunoreactive fibers and cell bodies. These results suggest that fulicin and other peptides derived from the fulicin precursor could regulate behaviors related to food intake, reproduction, and growth that are altered during the course of infection in this host-parasite system

    Changes in joint coupling and variability during walking following tibialis posterior muscle fatigue

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>The tibialis posterior muscle is believed to play a key role in controlling foot mechanics during the stance phase of gait. However, an experiment involving localised tibialis posterior muscle fatigue, and analysis of discrete rearfoot and forefoot kinematic variables, indicated that reduced force output of the tibialis posterior muscle did not alter rearfoot and forefoot motion during gait. Thus, to better understand how muscle fatigue affects foot kinematics and injury potential, the purpose of this study was to reanalyze the data and investigate shank, rearfoot and forefoot joint coupling and coupling variability during walking.</p> <p>Methods</p> <p>Twenty-nine participants underwent an exercise fatigue protocol aimed at reducing the force output of tibialis posterior. An eight camera motion analysis system was used to evaluate 3 D shank and foot joint coupling and coupling variability during treadmill walking both pre- and post-fatigue.</p> <p>Results</p> <p>The fatigue protocol was successful in reducing the maximal isometric force by over 30% and a concomitant increase in coupling motion of the shank in the transverse plane and forefoot in the sagittal and transverse planes relative to frontal plane motion of the rearfoot. In addition, an increase in joint coupling variability was measured between the shank and rearfoot and between the rearfoot and forefoot during the fatigue condition.</p> <p>Conclusions</p> <p>The reduced function of the tibialis posterior muscle following fatigue resulted in a disruption in typical shank and foot joint coupling patterns and an increased variability in joint coupling. These results could help explain tibialis posterior injury aetiology.</p

    A Golf Programme for People with Severe and Enduring Mental Health Problems

    Get PDF
    This article reports a pioneering golf programme for people with severe and enduring mental health problems. Following a discussion of the problems and possibilities of golf as a form of physical activity for this group, we outline the structure, organisation, and ethos of the golf programme. Through an analysis of qualitative case study data collected during the programme, we discuss the response to the programme from service users and mental health professionals. We conclude by highlighting aspects of the programme which were critical to its success and offering suggestions for further initiatives in this area

    The management of ocular allergy in community pharmacies in the United Kingdom

    Get PDF
    Background Ocular allergies frequently present in pharmacy practices. However, research into the actual management of ocular allergy in pharmacies is lacking. Objective To determine and quantify history and symptom questioning of a patient with presumed allergic conjunctivitis and management strategies employed by pharmacy staff in the UK. Method A mystery shopper technique was used to simulate an episode of allergic conjunctivitis in 100 community pharmacies across the UK. Results The mean number of questions asked by pharmacy staff to the patient was 3.5 ± 2.6, with a range of 0-10. The most common question was whether the patient had a history of allergies (45 %).Ninety-one percent advised on treatment, with the remaining 9 % directly referring to the patient's general practitioner (n = 4) or pharmacist(n = 4), but only two to their optometrist. The most common treatment suggested was sodium cromoglycate 2 % (50 %). However, many pharmacies advising treatment did not ask the patient's age (37 %), if they wore contact lenses (43 %), or gave dosage advice (43 %). Only 5 % of pharmacies advised follow up and 14 % suggested visiting a general practitioner and 1 % an optometrist if symptoms did not resolve with treatment. Conclusion There is a need for improved ophthalmological training for pharmacy staff with respect to the management of allergic conjunctivitis. © Springer Science+Business Media Dordrecht 2012
    • …
    corecore